Industry Insight
Discovery Technology
Analytical Laboratory Technology
Delivery Systems
Ingredients, Formulation and Finishing
View our other publications with free access to extensive archives


 28th November 2008 Bonfiglioli


Until recently the Methylene Blue Dye leak testing method has been used for blister packed tablets. This process, being messy, destructive as well as dependent on human errors, has now been finally replaced by a clean, precise, non-destructive leak tester that can be easily validated to detect, from cracks down to micro-leaks.

The compact LF-BLI machine is ideal for sample testing between the existing Blister Line and Cartoner Packing line. The blister packs are manually inserted on a test base, which may take up a number of blister packs depending on the size. A sensitive membrane is then sealed on the test base and a vacuum is applied, which (when set under a predetermined vacuum) will analyze the swelling of each blister cavity, thus indicating which blister pack is faulty. The machine will also indicate which cavity is leaking.

The main advantage of this machine is that no extra tooling is required for different size blister packs as the Sensitive membrane will adjust to any size and shape. The LF-BLI machine is fully computerized utilizing a SCADA platform. The software is easy to operate and includes utilities such as a products database, statistical reports etc. A printer may also be installed for printing test results and parameters. The technology is highly precise and fully validated.

Further information regards Bonfiglioli Engineering Leak Testers may be obtained from our website

Or contact us at:

Bonfiglioli Engineering S.r.l., Via Rondona 33, 44018 Vigarano, Pieve (Fe), Italy. E-Mail:, Tel: +39 0532 715631, Fax +390532 715625


Advair,Flovent,VentolinSymbicort,Serevent,FlonaseAstelin Rhinocort
IPTonline © 2004 The Pharmaceutical Technology Journal | Terms and Conditions | | UK Contacts |
Providing a platform of communication on new ideas, developments and innovations | UK Tel No. +44 20 77243456 | Back to top of page |