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Tosoh Bioscience GmbH Protein A based affinity chromatography is the industry standard for the capture of monoclonal antibodies (mAbs) in downstream processing. Affinity media offer high selectivity thereby yielding a high purity of the target molecule in one step. The rising fermentation titers in the production of monoclonal antibodies drive the focus on developing resins that increase downstream capacity and efficiency for these processes.

Tosoh Bioscience GmbH TOYOPEARL MX-Trp-650M, a new, mixed-mode chromatography resin combining a weak cation exchange and a hydrophobic interaction ligand for process scale chromatography applications is the latest addition to the TOYOPEARL product line. This resin, capable of being run much the same as a standard cation exchanger or in a more traditional HIC mode, truly lives up to the mixedmode moniker.

Tosoh Bioscience GmbH The importance of proper aggregate removal during polishing of a monoclonal antibody (mAb) for therapeutic use is beyond controversy. This application note intends to give you some insights into how you could start handling mAb polishing with the tryptophan immobilized ligand.

PolyPeptide Group The PolyPeptide Group is a privately-held group of manufacturing companies that provides proprietary and generic GMP-grade peptides for the pharmaceutical, cosmetic and biotechnological market.

Enamine Ltd Enamine Ltd, an Eastern Europe company, offers a wide range of products and services for your Drug Discovery programs. Screening compounds are in the main focus of Enamine production activity. Key products of Enamine also include building blocks, targeted and focused libraries. We provide fully integrated solutions for drug design and development: custom synthesis, contract research, lead generation and optimization programs.



ICX Nomadics ICx Nomadics takes early stage discoveries and inventions and drives them towards useful products. It conducts leading edge research and development with a wide range of sensing technologies







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