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Hot Cell-Culture Models

Functional drug candidate profiling using complex human organo-typic (HOT) cell-culture models, combined with systems biology-based pathway analysis, offers a promising way of reducing clinical drug failure.

By Manfred Schmolz at Experimental and Diagnostic Immunology (EDI) GmbH, and Thomas O Joos at the NMI Natural and Medical Sciences Institute, at the University of Tubingen (October 2008)

Keywords: Hot Co-Culture systems, Clinical failure rates, white-blood cultures, EDI-CO Gut model

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