The Identification of Bioisosteres as Drug Development Candidates
Molecular fields give a richer, more intuitive view of active molecules. Application of this technology to the search for bioisosteres results in relevant, non-obvious suggestions that make a significant impact on the drug development process.
By Tim Cheeseright at Cresset BioMolecular Discovery (March 2009)
Keywords: Bioisosteres in drug discovery, existing approaches, new approaches, choosing fragments, Cresset