A Multi-Mode, Cellular Platform for Investigation of the GPCR Signalling Network
Current understanding of GPCR membrane organisation is moving towards
a heterodimer model; a cellular technology platform developed for the study
of cell surface receptors will facilitate research into this new GPCR model, as
well as into challenging ligand binding studies, and second messengers and
phospho-ERK functional assays.
By Jean-Luc Tardieu at Cisbio Bioassays (March 2010)
Keywords: multi-mode, cellular platform, GPCR, signalling, network, membrane, heterodimer, combination technology, tag-lite, cell-lines