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In Vitro ADME Models: A Crystal Ball in a Petri Dish

The widespread use of three simple in vitro test systems has been largely responsible for the reduction in ADME-related clinical drug failures over the past 20 years. The need now is for more predictive, human-based in vitro

Chris Bode (September 2012)

Keywords: Absorption Distribution Metabolism and excretion (ADME) In vitro test systems Oral drug absorption Drug metabolism Drug-drug interactions Cytochrome P450 (CYP) 3A4

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