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Dutch Resolution in Theory and Practice

A review of the basic technique of Dutch Resolution – a variation on the classical Pasteur resolution via diastereomeric salts – including the role of nucleation inhibition, which has often been found to be involved in cases of successful resolution.

José Nieuwenhuijzen, Ton R Vries, Jan Dalmolen and Richard M Kellogg at Syncom BV, and Bernard Kaptein and Quirinus B Broxterman at DSM Pharma Chemicals (September 2005)

Keywords: Dutch Resolution variation Pasteur resolution diastereomeric salts nucleation inhibition

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