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A Co-Design Approach to Synthetic Route Selection

A co-design approach between R&D and manufacturing enables selection of the optimal synthetic routes in terms of cost and environmental advantages when it comes to commercial production.

Eric Cordi, Pfizer Chemical Research & Development, and Russell Schofield, Aspen Technology, Inc (March 2012)

Keywords: Synthetic route Active pharmaceutical ingredient (API) Process optimisation Production yield Production efficiency Manufacturing cost Green manufacturing Environmental metrics

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