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Genetic Immunization in the Development of mAb Therapeutics

Despite its attractions, DNA immunization is generally regarded as producing only low levels of antibodies - but recent advances offer new tools and strategies for the development of successful drug candidates against traditionally intractable targets.

Ross Chambers and Damon Hostin at Strategic Diagnostics, Inc (January 2009)

Keywords: Antigen fragmentation, Conformational epitopes, G-protein, genomic antibody technology

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