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Transgenic Technology: a Validated Approach for Large-Scale Manufacturing

Transgenic technology as a platform for the production of human recombinant therapeutics offers significant advantages with respect to capital expenditure and cost of goods. For the near future, the transgenic production of monoclonal antibodies represents an ideal technology for the basis of a successful biosimilars programme.

By Yann Echelard, William Gavin, Ashley Lawton, Carol Ziomek and Harry Meade at GTC Biotherapeutics Inc (July 2009)

Keywords: Transgenic technology, production, safety, human recominant therapeutics, monoclonal antibodies,

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