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Discovery and Development

Innovations in pharmaceutical Discovery and Development Including Bioinformatics, Proteomics, Nanotechnology, Formulation and Recipients, Extractables and Leachables

Articles

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Exploring new dimensions with spatial multi-omics

The implementation of spatial technologies advances disease research, but challenges must be overcome before spatial multi-omics becomes broadly accessible

17 March 2025Discovery and Development
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The evolution and future of DNA sequencing

The evolution of DNA sequencing – from Sanger to cutting-edge next generation approaches like Illumina, Nanopore and Single Molecule, Real-Time (PacBio) sequencing – has brought advances in speed, cost and accessibility. However, what challenges are faced in throughput scale-up, and what promise does automation hold for transforming genomics and personalised medicine?

17 March 2025Discovery and Development
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Overcoming delivery barriers to unlock the full potential of RNA-based medicine

While RNA molecules have demonstrated promising results as therapeutics for difficult-to-treat disease indications, their current limitations in terms of delivery mean their full potential is not being realised. How can this be overcome?

17 March 2025Discovery and Development
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The use of genetic information in precision medicine

The pharma industry needs a way to ensure the right therapies are getting to the right patients, in a timely and cost-effective way. How are advances in researchers’ understanding of genomics aiding not only precision medicine for rare diseases, but also for common health conditions?

17 March 2025Discovery and Development
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Advancing cell line development: how next-gen innovation meets industry needs

Cell line development is integral to research and biotherapeutic production, and so ensuring this process is as robust as possible through next-generation technology is in the industry’s best interests

6 December 2024Discovery and Development
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Harnessing spatial biology in drug discovery and development:navigating opportunities and challenges

How is current spatial biology being utilised in drug discovery and development for complex disease treatments, and how can it be improved?

6 December 2024Discovery and Development
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From ACGT to AI: visionary advances in oligonucleotide synthesis

Considering the importance and cost associated with oligonucleotide-based therapeutics, how can innovative computing imaging techniques be used to aid in the process, while also creating an audit trail and increasing the data derived from these experiments?

22 September 2024Discovery and Development
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How public/private partnerships in genomics are streamlining patient pathways and delivering value

Since the completion of the human genome project in 2003, there has been huge growth in the utilisation of genomics, but how can partnerships in this area be used to improve patient experience

7 July 2024Discovery and Development
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Next-generation size selection: accelerating the pace of gene synthesis

Synthetic biology has been a cornerstone in recent health advancements, including drug discovery, development and manufacturing, however there are challenges facing this market

7 July 2024Discovery and Development
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Non-viral gene therapies: GETting growth-factor-based healing right in orthopaedics

The development and use of novel gene therapy approaches is increasing. With the advent of innovative technologies using improved tropism and safer viral-based systems, and nanotechnology advancing non-viral delivery of nucleic acid vectors, there will be more gene-based products entering the market in near future

18 March 2024Discovery and Development
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Advancements in preclinical imaging: a look into the future of drug development

IPT talks with Jacob Tesdorpf at Revvity about the recent developments in preclinical imaging, from AI-enchanced analysis to refined disease models

18 March 2024Discovery and Development
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Novel biosensors for enhanced antimicrobial delivery efficiency

The World Health Organization (WHO) has recognised the scarcity of new antimicrobial agents in the clinical pipeline. The prevailing approach to combatting antimicrobial resistance cannot solely rely on developing new drugs. Instead, we must seek ways to better understand and more efficiently use the drugs already at our disposal.

20 December 2023Discovery and Development